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This glucose-dependent mechanism significantly reduces the risk of hypoglycaemia compared with some other diabetes medicines
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In a phase 2 trial, survodutide, an injectable dual glucagon/GLP-1 receptor agonist, produced significant mean weight losses: −6.2%, −12.5%, −13.2%, and −14.9% at 0.6 mg, 2.4 mg, 3.6 mg, and 4.8 mg, respectively, compared to −2.8% in the placebo group [96]